Blood Grouping of Human Red Cells with I-131 Labelled Antibody

Reaction of I-131 trace labeled human anti-Rho(D) with red cells.

Biodistribution and pharmacokinetics of I-131 labelled 4-iodophenylacetic acid.

Phenylacetate has been reported to have a potent anti-proliferative and anti-differentiating effect in haematological malignancies and in solid tumours at non-toxic concentrations. This study is a preliminary investigation of 131I-radiolabelled 4-iodophenylacetic acid as a potential radiopharmaceutical equivalent. Radiolabelling by isotope exchange gave a radiochemical yield of 53 ± 6 %, and a ...

The Preparation of I-131-labelled Human Growth Hormone of High Specific Radioactivity.

Burns, J. J., Evans, C. & Trousof, N. (1957). J. biol. Chem. 227, 785. Conchie, J., Findlay, J. & Levvy, G. A. (1959). Biochem. J. 71, 318. Conney, A. H., Bray, G. A., Evans, C. & Burns, J. J. (1961). Ann. N.Y. Acad. Sci. 92, 115. Dixon, M. & Webb, E. C. (1958). Enzymes, p. 78. London: Longmans, Green and Co. Ltd. Dowben, R. M. (1959). Biochim. biophys. Acta, 31, 454. Findlay, J., Levvy, G. A. ...

Effects of High Doses of X-Ray on Hematological Parameters and Morphology of Red Blood Cells in Human Blood

Introduction: The aim of the current study was to investigate the effects of X-ray radiation on some hematological parameters, morphology of red blood cells (RBC) and erythrocyte sedimentation rate (ESR) analysis of human blood using computed tomography (CT) scanner. Material and Methods: For the purpose of the study, 5 ml of wholeblood was drawn from vein puncture of 28 healthy people and div...

Carcinomatous meningitis: antibody-guided therapy with I-131 HMFG1.

Seven patients with carcinomatous meningitis were administered intrathecal I-131 labelled monoclonal antibody HMFG1. Clinical responses were seen in two patients, with a long term survivor at 32 months. Aseptic meningitis occurred in 4/7 patients, but more serious toxicity was observed in the form of seizures (2/7 patients) and myelosuppression (3/7 patients). Partial obliteration of the subara...